Advances in asthma, asthma-COPD overlap, and related biologics in 2018
نویسندگان
چکیده
منابع مشابه
The Asthma-COPD Overlap Syndrome.
Although in textbooks asthma and chronic obstructive pulmonary disease (COPD) are viewed as distinct disorders, there is increasing awareness that many patients have features of both. This article reviews the asthma-COPD overlap syndrome.
متن کاملThe Asthma-COPD Overlap Syndrome
Asthma and Chronic Obstructive Pulmonary Disease (COPD) are pulmonary disorders characterized by various degrees of airflow limitation, inflammation and tissue remodeling. Bronchial asthma, an allergic disease that develops in childhood, is physiologically characterized by reversible airflow obstruction. It has an episodic course and a generally favorable prognosis, as it responds well to anti-...
متن کاملInflammatory biomarkers in asthma-COPD overlap syndrome
BACKGROUND The clinical phenotypes and underlying mechanisms of asthma-COPD overlap syndrome (ACOS) remain elusive. This study aimed to investigate a comparison of COPD patients with and without ACOS, focusing on inflammatory biomarkers, in an outpatient COPD cohort. METHODS We conducted a cross-sectional study analyzing prospectively collected data from the Ishinomaki COPD Network registry. ...
متن کاملLongitudinal changes in clinical outcomes in older patients with asthma, COPD and asthma-COPD overlap syndrome.
BACKGROUND The progression of obstructive airway diseases (OADs) including asthma, chronic obstructive pulmonary disease (COPD) and asthma-COPD overlap syndrome in older adults is not well understood. OBJECTIVE To examine the prognosis of OADs and to identify potential determinants for longitudinal changes in clinical outcomes. METHODS We consecutively recruited 99 older adults (>55 years) ...
متن کاملComparison of in-hospital mortality in patients with COPD, asthma and asthma-COPD overlap exacerbations.
BACKGROUND AND OBJECTIVE Obstructive airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD), have airflow limitation associated with chronic inflammation. Using a national inpatient database in Japan, we aimed to evaluate factors affecting in-hospital mortality in patients with asthma, COPD or asthma-COPD overlap (ACO). METHODS We retrospectively collected data for i...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2019
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2019.08.021